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The thyroid glands are two very small glands that sit either side of your cat’s windpipe. These glands use dietary iodine to make thyroid hormones. In turn, these hormones help regulate important body functions. You can picture the thyroid glands like the coal furnace on a steam train. When you need more heat or speed, the metabolism is cranked up, like shovelling coal into the furnace. Thyroid hormones help regulate:
- Metabolism
- Body temperature
- Blood pressure
- Heart rate
- Gastrointestinal (bowel) function

What is feline hyperthyroidism?
Hyperthyroidism is a common feline endocrine disorder, most often diagnosed in older cats over the age of 10. It is usually the result of a benign tumour (also called hyperplasia) in one or both of the glands. These tumours produce an excess of thyroid hormones and the metabolism goes into overdrive.
Left untreated, hyperthyroidism can have serious, sometimes fatal, consequences on vital organs like the heart and kidneys. However, the good news is this disease is highly manageable and can be controlled with proper veterinary care.
Warning signs and symptoms of feline hyperthyroidism
Signs of hyperthyroidism can vary in severity depending on how long a cat has been ill. As the metabolism is being cranked up by all these extra hormones, the most common signs and symptoms are:
- Weight loss
- Increased appetite
- Diarrhoea and/or vomiting
- Increased thirst
- Poor skin and coat condition
- Hyperactivity
- Increased vocalisation
Cats with chronic kidney disease and diabetes mellitus exhibit some signs similar to hyperthyroidism. Your veterinarian may also need to perform tests for these diseases to ensure an accurate diagnosis. Of course, in older cats, it’s also not uncommon to have one or more of these diseases going on at any one time.
Treatments for cats with hyperthyroidism
There are four potential options for managing cats with hyperthyroidism:
Nutrition. Limiting dietary iodine intake reduces thyroid hormone production. This therapeutic food still has all the iodine an adult cat needs, but not enough to allow an overproduction of the hormone.
Pros:
- No need to medicate your cat. Your cat needs to be fed anyway, so incorporating a treatment option makes sense.
- No chance of side effects.
- No need to hospitalise your cat.
Cons:
- Some cats may be picky eaters and not like the food. If your cat regularly eats elsewhere, then the food may not work.
Medication. Antithyroid drugs inhibit the production of thyroid hormones.
Pros:
- No need for hospitalisation.
- Effective.
Cons:
- Some cats are difficult to medicate.
- These drugs can have significant side effects in some cats, such as intense facial itching, skin lesions, gastrointestinal signs and some moderate to severe anaemia and other blood changes.
Radioactive iodine therapy. This involves using radiation to destroy abnormal thyroid tissue.
Pros:
- Effective
- Usually no need to medicate long-term.
Cons:
- Expensive.
- Only a few centres offer this treatment so your cat may have to travel a long distance.
- It’s likely that centres will ask that your cat stays with them for some time after treatment. However this is in the best interest of your household and your cat. The radioactive material used for the treatment quickly makes its way into their urine and faeces, so these will need to be disposed of safely before they’re able to return home to you.
Surgery. This involves removal of diseased thyroid tissue.
Pros:
- Curative. If the tumour is a rare malignancy, medication and food will not tackle it but surgery will, if the tumour has not spread already.
Cons:
- Normal risks associated with surgery and anaesthesia, especially in older cats.
- Your cat will need to be hospitalised for a day or two, which may be stressful.
- Occasional complications if the adjacent parathyroid glands are damaged. This can lead to problems with calcium metabolism that may be severe.
There is no one option that will suit every cat. With all of these options, you will need to do some longer-term monitoring of thyroid levels and renal function through regular blood testing. As you can see, each treatment option has its pros and cons, so have a discussion with your veterinarian and look at your and your cat’s lifestyles. Together, you can pick the right option for you and your cat.
Reviewed by Dr. Hein Meyer, DVM, PhD, Dipl-ECVIM-CA and Dr. Emma Milne BVSc FRCVS.